Fig. 4. Effect of SFN and As on the immunohistochemistry expression of Bcl-2 in control and experimental rats. (A) Control rats: hepatocytes are strongly stained (SS) with the anti-apoptotic Bcl-2 antibody. (B&C) As treated rats show the decreased immunoreactivity (DIR) of Bcl-2 antibody in the liver tissue. (D) As treated rats pre-treated with SFN shows markedly increased immunoreactivity (MII) of Bcl-2 in liver tissue. (E) SFN treated rats also showed similar to that of control liver tissue appearance. Magnification ×200.